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@SaraSuliman is an assistant professor in the Department of Experimental Medicine at UCSF. Her lab uses multiple approaches to identify candidate tuberculosis (TB) risk pathways and to determine their role in TB progression. For our latest #PeopleAndIdeas, we caught up with Sara to talk about how she got interested in science, what she’s currently working on, and what she thinks about the future o
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On our May cover: Qin et al. (https://doi.org/10.1084/jem.20220776) develop a genome-editing tool that combines the versatility of prime editors and unconstrained PAM requirement of SpRY, which is able to rescue retina functionality and restore vision in mice. The cover shows a section of a Pde6bT to C mouse retina immunostained for GFP (green), rhodopsin (red), and nuclei (blue).
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Our February cover shows a cortical section immunostained for CD31 and αSMA to identify capillary-like arteriovenous connections in mice.
Nielsen et al. (https://rupress.org/jem/article/220/2/e20211390/213722/Endothelial-Rbpj-deletion-normalizes-Notch4?utm_source=mastodon) show that brain arteriovenous malformations induced by constitutively active Notch4 in mice are normalized following deletion
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We're pleased to present a special collection highlighting recent immunology research articles. The collection covers a range of topics including immunometabolism, mucosal immunology, lymphocyte activation, immune cell differentiation and residency, inflammation, host-parasite interactions, tumor immunology and immunodeficiencies. We hope you enjoy reading the collection and welcome your feedback!
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🔥 Top post: @SaraSuliman is an assistant professor in the Department of Expe · 9 likes + reposts
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@SaraSuliman is an assistant professor in the Department of Experimental Medicine at UCSF. Her lab uses multiple approaches to identify candidate tuberculosis (TB) risk pathways and to determine their role in TB progression. For our latest #PeopleAndIdeas, we caught up with Sara…
Our September Issue is out! The cover image shows immunofluorescence staining of nuclei (DAPI, blue), pan-cytokeratin (red), and MHC-II (green) in metastatic lymph nodes in formalin-fixed paraffin-embedded specimens from breast cancer pati…
Our August cover shows a sagittal plane confocal image of a naive knee from CX3CR1-eGFP Ly6G-tdTomato double reporter mouse containing resident macrophages and no neutrophils (pan-macrophage CD68, cyan; lining macrophage VSIG4, magenta; CX…
Oral TRM reactivation elicits gingival inflammation. Our July cover shows increased OT-I T cells (white) and pan-leukocytes (red) in buccal mucosa of a novel viral-prime, epitope-pull (VPEP) mouse model, after oral SIIN peptide swabbing. N…
On our June cover: DNASE1/DNASE1L3 double-knockout (DKO) mice were infected with S. aureus, and their kidneys were examined by immunohistochemistry 72 h later. Sections were stained with DAPI and antibodies against S. aureus (green) and Ly…
On our May cover: Qin et al. (https://doi.org/10.1084/jem.20220776) develop a genome-editing tool that combines the versatility of prime editors and unconstrained PAM requirement of SpRY, which is able to rescue retina functionality and re…
On our April cover: Petkova et al. (https://doi.org/10.1084/jem.20220741) identify a new Ptx3-positive immunoregulatory subtype of lymphatic endothelial cells, iLECs, that drive oncogenic PI3K-driven lymphatic malformations. The cover show…
On our March cover: Kaiser et al. show that regulatory T cells infiltrate sites of active viral infection and influence epithelial repair (https://bit.ly/3KMFS2l).
The image shows a lung section of a mouse infected with influenza-labeled (…
Gut microbiota biofilms: From regulatory mechanisms to therapeutic targets.
In this Viewpoint, Andre Buret and Thibault Allain discuss the mechanisms that regulate gut microbiota biofilms integrity and highlight the importance of studying…
The animal model for experimental encephalomyelitis, first published 90 yr ago, continues to illuminate mechanisms of disease. The model, initially developed to understand how smallpox triggers neuroinflammation on rare occasions, now move…
Our February cover shows a cortical section immunostained for CD31 and αSMA to identify capillary-like arteriovenous connections in mice.
Nielsen et al. (https://rupress.org/jem/article/220/2/e20211390/213722/Endothelial-Rbpj-deletion-norm…
We're pleased to present a special collection highlighting recent immunology research articles. The collection covers a range of topics including immunometabolism, mucosal immunology, lymphocyte activation, immune cell differentiation and …
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